Theme Co-Lead for Liver Disease, Multimorbidity and Lifestyle
Prof Quentin M. Anstee holds the Ruth & Lionel Jacobson Chair of Personalised Medicine and is the Dean of Research & Innovation in the Faculty of Medical Sciences, Newcastle University, UK. A practicing clinician, he is also an Honorary Consultant Hepatologist in the Liver Transplant Unit at Newcastle’s Freeman Hospital, where he leads one of the largest Metabolic-dysfunction Associated Steatotic Liver Disease (MASLD), formerly called Non-Alcoholic Fatty Liver Disease (NAFLD), clinical services in the U.K. He trained in medicine at University College London where he was awarded a First Class Honours degree and won First Prize in Medicine in the final MB BS examination.
Prof Anstee’s translational research has made major contributions across the pathophysiology, natural history, diagnosis and treatment of MASLD. His work has provided key insights into temporal changes in steatohepatitis during disease evolution, identified genetic and epigenetic modifiers of liver disease progression and hepatocellular carcinoma risk, and has substantially advanced the field of biomarker development in liver disease. He has coordinated several major international research consortia studying pathogenesis and developing/validating accurate biomarkers to assist the diagnosis, risk-stratification and monitoring of patients with MASLD including: ‘EPoS’ Elucidating Pathways of Steatohepatitis (EU H2020 funded €6 million, 2015-2019) and ‘LITMUS’ Liver Investigation: Testing Marker Utility in Steatohepatitis (EU IMI2 funded €47.3 million, 2017-2024). He leads the European MASLD Registry and is the chief investigator of multiple ongoing clinical trials assessing new medical therapies for MASLD. He is an NIHR Senior Investigator and has been named as one of the world’s most influential researchers in the Web of Science list of Highly Cited Researchers, amongst the top 1% of scientists by citation metrics. He is an Associate Editor of the Journal of Hepatology.
Newcastle University profile