My study is on the cognitive symptoms that patients with Primary Biliary Cholangitis (PBC) experience. PBC is a condition that affects the liver, but several patients have also reported cognitive symptoms. The understanding of this is poor, and the pathophysiology is unknown. The aim of our study is to objectively assess the PBC patients with or without symptoms, using CANTAB neuropsychiatric battery and functional MRI imaging. The findings from the study will help us understand the cognitive symptoms in PBC patients.
By increasing our understanding of this lesser-known symptom, we hope to be able to develop the therapeutic treatment for the symptom.
For the study, we worked with people diagnosed with PBC. Their input was essential in helping us gather data to contribute to our study. Our clinical research team provided information to potential participants at their regular autoimmune liver clinic appointments that took place at Newcastle Hospitals. From here, the patients could opt into the study if it was suitable for them. We were grateful to those who volunteered and attended additional clinic visits to participate in our study.
As an NIHR funded trainee, I had access to research training and mentorship. I also had opportunities to network with trainees working in other areas. The experience during these years was invaluable.
I am now back to my clinical training. I will now apply the academic knowledge and skills that I have learned as a BRC trainee, in my clinical practice and clinical research projects.