The workstream aims to:

• Deliver and evaluate scalable, real-world interventions that prevent MLTC or improve outcomes for those living with MLTC.
• Shape national and international evidence to inform policy and regulation for MLTC research and care.
• Secure sustainable funding by strengthening relationships with current funders and driving a shift from single-disease research models toward approaches that embed MLTC as a central priority.
• Strengthen and expand the MLTC research community, supporting early-career researchers.
• Ensure inclusive representation of people with MLTCs across research and clinical trials.

The workstream will identify opportunities for large-scale collaborative intervention projects around the translational circle to prevent or treat the causes and consequences of MLTC, develop appropriate funding bids, and drive the delivery of successful projects across multiple areas of NIHR infrastructure.