Authors:
Alivernini S, Cañete JD, Bacardit J, Kurowska-Stolarska M.

Abstract: 
Current treatments for rheumatoid arthritis aim to achieve and maintain disease remission, which is characterized by the absence of symptoms of inflammation. However, remission is often fragile, with about 50% of patients experiencing disease flares after reducing or stopping medication, representing a burden for both patients and clinicians. Although some predictors of flare exist, they do not confidently predict flare for most patients with rheumatoid arthritis in remission. Recent studies suggest that deconvolution of patients’ synovial tissue cellular and molecular signatures may offer more accurate prediction models.

Nat Med 2024 Apr;30(4):925-926

doi: 10.1038/s41591-024-02818-w

PMID: 38361121

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